I'm collecting golden fingers from all over the world

Generally speaking, new drugs need to conduct phase I, phase II, and phase III clinical trials before they are launched on the market.

Generally, the first-phase trial, also called the clinical pharmacology and toxicology trial period, is a preliminary clinical pharmacology and human safety evaluation test for a new drug, including human tolerance testing and human drug metabolism kinetics measurement, that is, drug absorption , distribution, metabolism, elimination, etc., and observe the safety of the drug.

New anti-tumor drugs are different from other non-tumor drugs. Due to their high cytotoxicity, tumor patients usually need to be selected as subjects; the number of people in phase II trials will increase, and the applicable population, efficacy and safety of the drugs will be further studied; phase III trials often Compared with the current best treatment model, only when the efficacy of a drug exceeds that of existing better drugs can it become an effective new drug and be approved for marketing.

If we calculate the time from the beginning of the first-phase trial, it will take 5-10 years until the new drug is approved for marketing. Most of them will take 10 years, and some will even be longer, up to 15 years.

After a drug is approved for marketing, it still needs to conduct phase four clinical trials. Phase IV clinical trials are also clinical monitoring periods to monitor the efficacy of new drugs as well as the incidence and extent of adverse reactions. If the efficacy is unsatisfactory, or serious adverse reactions occur with a high incidence rate, the regulatory authorities will recall the new drug and withdraw it from the market.

This is the general launch time for new anti-tumor drugs.

That is to say.

If these patients with mid- to late-stage cancer wait for more than ten years, they will have the opportunity to be prescribed [redizumab] by their doctors - if they can survive until that time.

And unless the cancer is completely cured, these patients with intermediate and advanced cancer will not survive for more than ten years.

The vast majority of them may not survive a year.

So the doctor's answer was unacceptable to them.

They strongly requested to obtain [ledizumab]!

Doctors and hospitals have no choice but to comfort patients and their families with sincere words, saying that the drug [redimab] is still in the first phase of clinical trials. There is currently little medical data, the side effects and dangers are unclear, and the medical effects are unclear. It is not yet determined. For the safety of patients' lives and property, we still have to wait until sufficient clinical trial data is available.

After all, the side effects of some drugs are not obvious, and it is not uncommon for drugs to have side effects discovered many years after they have been on the market.

For example, the once miracle drug——[Analgin]!

[Analgin] is an antipyretic and analgesic drug invented by the Germans. It was launched as an over-the-counter drug in 1922 and was produced and launched in China in 1950.

Because of its low price and excellent effect, [Analgin] is very popular in countries around the world.

But half a century after it was launched, countries around the world have discovered that it has too many side effects.

This drug will cause a decrease in granulocytes in the blood, thereby reducing immunity and increasing the risk of infection. It may also lead to autoimmune hemolysis, aplastic anemia, allergies and other problems, and even a large number of patient deaths.

Therefore, for safety reasons, the risks outweigh the benefits, so many countries around the world have banned or restricted the use of metamizole.

Many Western medicines on the market have this situation.

Side effects that were not found in clinical trials were only discovered after long-term, large-scale use on the market.

Therefore, new vocabulary is often added to the adverse reactions column of Western medicine instructions.

In this regard, Western medicine cannot compare with Chinese medicine.

In the instructions for traditional Chinese medicine, adverse reactions and contraindications only need to be stated as unclear.

As long as [it’s not clear yet], there are no [side effects], it’s perfect!

Like a certain compound of licorice tablets.

Although it is also cheap and effective as a cough suppressant.

But its main ingredient that acts as a cough suppressant is opium powder.

This stuff can become addictive if you eat too much! Long-term continuous consumption can lead to drug dependence.

In addition, people with high blood pressure who take this medicine may be at risk of increased blood pressure, hypokalemia, edema and other problems.

never mind.

Don't talk about this.

Back to topic.

Under normal circumstances.

These concerns of oncologists are not unfounded.

But that's for normal people.

These cancers are in the middle and late stages. They have no surgical treatment and can only receive conservative treatment. They are almost dying. If there is a glimmer of hope, they will never let it go.

So their reaction was relatively large.

They dare not mess with [Xuanhu Technology], the [Magic Medicine Research and Development Company] that controls their life and death.

Therefore, these patients and their families can only put the pressure on doctors and hospitals, two [vulnerable groups] that are comparable to banks.

The hospital is under a lot of pressure.

at the same time.

The surprising effect of [ledimumab] on cancer has also been spread in society through the social relationships between cancer patients and their attending doctors.

Following the video above [Douyin] [After taking new anti-cancer drugs, many terminal cancer patients can no longer detect cancer cells in their bodies, another terminal disease has been overcome by humans], the entire public opinion was instantly detonated.

Countless people reposted the discussion and reported on major social media.

Many people have learned from this that a new anti-cancer drug has appeared in the Yue Provincial Cancer Hospital that can effectively treat most cancers, and the efficacy is amazing.

Because the popularity was so high, the Yue Provincial Cancer Hospital had to explain that its hospital was assisting [Xuanhu Technology] in conducting clinical trials of a new broad-spectrum anti-cancer drug, but because the trial time was short, the effect was still uncertain.

As soon as this explanation came out, the popularity became even higher. It turned out to be true!

A large number of media reporters and patients’ family members flocked to the Yue Provincial Cancer Hospital.

Most of the family members of the patients have terminal cancer, looking for hope.

Media reporters want to report in depth and learn more relevant news.

The Yue Provincial Cancer Hospital was surrounded and its normal work was severely disrupted.

Moreover.

In this experiment, the most accurate data is in the hands of [Xuanhu Technology].

If they can't find [Xuanhu Technology], they will only find [hospitals] for vulnerable groups.

The hospital had no choice but to refuse interview requests from major reporters.

But of course these uncrowned kings will not give up here. Instead, they will cross the sea and show their magical powers.

If hospitals and doctors don't accept interviews, they will look for patients who have entered the experimental group.

Some patients in the experimental group who were on the verge of life and death wanted to be interviewed by reporters.

They hope that through reporters, they can put more pressure on the hospital and have a greater impact, so that they can take this medicine before they die without having to wait [more than ten years].

Although this drug has not undergone long-term clinical trials, it is not known what side effects it has.

However, these patients who are in the advanced stage of cancer and have no chance to join the [redizumab] experimental group or who have joined but have no effect will all die.

What’s the point of telling them about side effects?

Meaning is for living people.

Dead people don't know how to be particular.